Glucose metabolism: The canary in the coal mine

June 11th, 2009  |  Published in Stumpblog  |  2 Comments

Altered blood sugar metabolism can help predict — and perhaps prevent, or delay — the onset of Type 2 diabetes (aka adult onset diabetes). T2D is an emerging health epidemic with close ties to cardiovascular disease. Approximately 85-95% cases of diabetes are T2D.

From Medpage Today:

Insulin sensitivity, beta-cell function, and blood glucose may provide telltale signs of impending type 2 diabetes up to five years before onset, researchers affirmed.

The traditional marker for diabetes and prediabetes diagnosis — fasting blood glucose — shot up in the three years prior to diabetes onset, Adam G. Tabák, M.D., of University College London, and colleagues found in a 13-year study of British civil servants.

But beta-cell function abnormalities emerged three to four years before onset and insulin sensitivity fell sharply over the five years before diagnosis, they reported here at the American Diabetes Association meeting and simultaneously online in The Lancet.


  1. chris says:

    June 13th, 2009at 8:05 am(#)

    this is why i bought a home blood glucose meter. not too expensive for piece of mind and faster results than going to the md.

  2. Matt S says:

    June 13th, 2009at 3:29 pm(#)

    Diabetes is a really frightening pandemic.

    It’s good to know research is being done to recognize the early signs.

    I wonder at what point people will look at treating some of the root causes of the disease? Especially when prevention can entail proper diet and exercise(citation below).

    1) Santaguida PL, Balion C, Hunt D, et al. (August 2005). “Diagnosis, prognosis, and treatment of impaired glucose tolerance and impaired fasting glucose” (PDF). Evid Rep Technol Assess (Summ) (128): 1–11. PMID 16194123.

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